Autoimmunity
III. Systemic (Non-Organ specific) Autoimmune diseases
This  group includes conditions characterized by immune response against a variety of  self-antigens and damage to several organs and tissue systems.
               (i)  Systemic lupus erythematosus
                           This is a  chronic, multisystem disease with remissions and exacertations, terminating  fatally.
               (ii)  Rheumatoid Arthritis
               This is a systemic poly arthritis  with muscle wasting and subcutaneous nodules, commonly associated with  serositis, myocarditis, vasculitis and other disseminated lesions. It is found  more commonly in women.
  (iii)  Polyartheritis
              This is a  necrotizing angiitis involving medium sized arteries, ending fatally due to  coronary thrombosis, cerebral hemorrhage or gastrointestinal bleeding.
  (iv)  Sjogren syndrome
        This is a triad of conjuctivities  sicca, dryness of the mouth, with or without salivary gland enlargement, and  rheumatoid arthritis.